PTP4A2

Alternative Names: HH7-2, HH13, HU-PP-1, OV-1, PRL2, PRL-2, ptp-IV1a, ptp-IV1b, PTP4A, PTPCAAX2.

PTP4A2 is a member of the PTP protein family and is found in early endosomes where it plays a role in cellular activities. It interacts with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II) to regulate GGT II activity. Overexpression of PTP4A2 in mammalian cells leads to a transformed phenotype, implicating it in tumorigenesis.

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  • Sku: PSB-enz-558-2µg
  • Vendor: ProSpec-Tany
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Safety Data Sheet
UniProt Listing
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Product Details

Product Description

Recombinant Human Protein Tyrosine Phosphatase Type IVA Member 3 is a member of the protein tyrosine phosphatase family, specifically belonging to the Type IVA subgroup. This enzyme plays a role in the regulation of various cellular processes by dephosphorylating tyrosine residues on target proteins. Recombinant Human Protein Tyrosine Phosphatase Type IVA Member 3 has a molecular weight of approximately 37 kDa, making it suitable for use in various biochemical studies and drug development research.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 N/A
Structure Homodimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Frozen
Formulation The PTP4A2 (0.5mg/ml) protein solution contains 20mM Tris-HCl, pH-8, 1mM EDTA and 10% Glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMNRP APVEISYENM RFLITHNPTN ATLNKFTEEL KKYGVTTLVR VCDATYDKAPVEKEGIHVLD WPFDDGAPPP NQIVDDWLNL LKTKFREEPG CCVAVHCVAG LGRAPVLVAL ALIECGMKYE DAVQFIRQKR RGAFNSKQLL YLEKYRPKMR LRFRDTNGHC CVQ.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution
​

References

Not Available
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PTP4A2
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