PTHrP N15

Alternative Names: Parathyroid Hormone 2, PTH2, Tuberoinfundibular 39 Residue Protein, TIPF39.

PTHrP is a potent and specific agonist of PTH2R, leading to activation of adenyl cyclase and an increase in intracellular calcium levels. It also promotes activation of protein kinase C beta, recruitment of beta-arrestin, and internalization of PTH2R. Furthermore, PTHrP inhibits cell proliferation by activating PTH2R, while also playing a role in nociception and spermatogenesis.

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  • Sku: PSB-hor-005-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human Parathyroid Hormone Related Protein N15 Labeled is a member of the parathyroid hormone family, a group of proteins that play a key role in regulating calcium and phosphate levels in the body. This specific protein has a molecular weight of approximately 15 kDa and is labeled for research purposes. Its precise function and potential applications in the field of molecular biology make it a valuable tool for studying various physiological processes related to bone metabolism and calcium homeostasis.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Lyophilized
Formulation PthRp N15 protein was lyophilized from a 0.2µm filtered concentrated solution in 1xPBS, pH 7.4.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

AVSEHQLLHD KGKSIQDLRR RFFLHHLIAE IHTAEIRATS EVSPNSKPSP NTKNHPVRFG SDDEGRYLTQ ETNKVETYKE QPLKTP.

Storage Instruction

Lyophilized PTHrP N15 although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution PTHrP N15 should be stored at 4C between 2-7 days and for future use below -18C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in 10mM HAc to a concentration of 0.1-1.0 mg/mL. Further dilutions should be made in appropriate buffered solutions.

References

Not Available

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PTHrP N15

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