PTHrP

Alternative Names: Parathyroid Hormone 2, PTH2, Tuberoinfundibular 39 Residue Protein, TIPF39.

PTHrP is a potent agonist of PTH2R, activating adenyl cyclase and increasing intracellular calcium levels. It also stimulates protein kinase C beta activation, beta-arrestin recruitment, and PTH2R internalization. PTHrP inhibits cell proliferation, activates nociceptors and nociceptive circuits, and plays a role in spermatogenesis.

Skip to product information
  • Sku: PSB-hor-004-10µg
  • Vendor: ProSpec-Tany
$60.00 USD
 per 
Shipping calculated at checkout.

Contact us directly for international purchases.

Title

Product Details

Product Description

Recombinant Human Parathyroid Hormone Related Protein (rhPTHrP) is a protein belonging to the parathyroid hormone family. It plays a crucial role in regulating calcium and phosphate levels in the body. With a molecular weight of approximately 9.5 kDa, rhPTHrP is involved in various physiological processes, including bone development and maintenance. This recombinant protein is commonly used in research and therapeutic applications for its ability to modulate bone metabolism and mineral homeostasis.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 97.0% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Lyophilized
Formulation PthRp protein was lyophilized from a 0.2µm filtered concentrated solution in 1xPBS, pH 7.4.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

AVSEHQLLHD KGKSIQDLRR RFFLHHLIAE IHTAEIRATS EVSPNSKPSP NTKNHPVRFG SDDEGRYLTQ ETNKVETYKE QPLKTP.

Storage Instruction

Lyophilized PTHrP although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution PTHrP should be stored at 4C between 2-7 days and for future use below -18C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized PTHrP in sterile 18MΩ-cm H₂O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available

View full details

PTHrP

SUBHEADING

Recently viewed products