PTH (7-84)

Alternative Names: Parathormone, PTH, Parathyrin

Parathyroid hormone (PTH) is a polypeptide containing 84 amino acids secreted by the parathyroid glands. It functions to increase calcium levels in the blood, contrasting with calcitonin which decreases calcium levels. PTH achieves this by interacting with parathyroid hormone receptors in three main areas of the body. In bones, PTH stimulates the release of calcium by promoting bone resorption through osteoclast activity. In the kidneys, PTH enhances calcium reabsorption in the distal tubules and thick ascending limb. Lastly, in the intestine, PTH boosts calcium absorption by increasing vitamin D production and enzyme activity necessary for calcium uptake.

  •
  • Sku: PSB-hor-011-100µg
  • Vendor: ProSpec-Tany
$220.00 USD
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Safety Data Sheet
UniProt Listing
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Product Details

Product Description

Recombinant Human Parathyroid Hormone (7-84) is a synthetic form of the parathyroid hormone that belongs to the family of hormones responsible for regulating calcium and phosphate levels in the body. This hormone has a molecular weight of approximately 9.5 kDa and plays a crucial role in bone metabolism and calcium homeostasis. Recombinant Human Parathyroid Hormone (7-84) is commonly used in the treatment of osteoporosis to stimulate bone formation and increase bone mineral density.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System E. coli
Purity 97.0% by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 N/A
Structure Homodimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Lyophilized
Formulation Lyophilized from a 0.2 µm filtered concentrated solution in PBS, pH 7.4.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

LMHNLGKHLN SMERVEWLRK KLQDVHNFVA LGAPLAPRDA GSQRPRKKED NVLVESHEKS LGEADKADVN VLTKAKSQ.

Storage Instruction

Lyophilized PTH (7-84) although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution PTH (7-84) should be stored at 4C between 2-7 days and for future use below -18C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized PTH (7-84) in sterile 18MΩ-cm H₂O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available
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PTH (7-84)
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