PTH (7-34)

Alternative Names: PTH/PTHrP receptor antagonist, PTHrP analog, PTHR, MGC138426, MGC138452

Parathyroid glands secrete polypeptide hormones that regulate calcium levels in the body by releasing calcium from bones, increasing intestinal absorption, and promoting renal reabsorption. This process is crucial for bone metabolism. Parathyroid hormone is released when calcium levels are low and is antagonized by calcitonin. PTH (7-34), a receptor antagonist, has been shown to stimulate hair growth and epidermal proliferation in mice.

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  • Sku: PSB-hor-266-100µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Parathyroid Hormone (7-34) is a synthetic form of the parathyroid hormone, belonging to the family of hormones responsible for regulating calcium and phosphorus levels in the body. With a molecular weight of approximately 4117.5 Daltons, this hormone plays a crucial role in bone metabolism and calcium homeostasis. Its synthetic form is often used in the treatment of osteoporosis to stimulate bone formation and increase bone mineral density.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 97.0% by SDS-PAGE
Activity
The activity calculated by UMR106 cell/cAMP method corresponding to a specific activity of 10,000 Units/mg. The activity calculated by UMR106 cell/cAMP method corresponding to a specific activity of 10,000 Units/mg.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Dimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Lyophilized
Formulation The protein (1 mg/ml) was lyophilized after extensive dialyses against 20mM PBS pH-7.0 and 150mM NaCl.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

LMHNLGKHLN SMERVEWLRK KLQDVHNF.

Storage Instruction

Lyophilized Parathyrin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution PTH should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized PTH in sterile 18MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available

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PTH (7-34)

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