PSMD9

Alternative Names: 26S proteasome regulatory subunit p27, p27, PSMD9, Rpn4, 26S proteasome non-ATPase regulatory subunit 9

PSMD9 is a proteinase complex consisting of a 20S core and a 19S regulator. It functions as a chaperone in the assembly of the 26S proteasome, specifically in the formation of the base subcomplex of the PA700/19S regulatory complex. PSMD9 is initially part of an intermediate module with PSMC6 and PSMC3, known as the modulator trimer complex, but is released during further assembly.

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  • Sku: PSB-enz-666-5µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Proteasome 26S Subunit, Non-ATPase 9 is a protein complex belonging to the proteasome family, responsible for degrading damaged or misfolded proteins within the cell. With a molecular weight of approximately 28 kDa, this subunit plays a key role in the regulation of protein turnover and maintaining cellular homeostasis. Its function is essential for proper cellular function and viability.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
27.1 kDa
Structure Trimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The PSMD9 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSMSDEEAR QSGGSSQAGV VTVSDVQELM RRKEEIEAQI KANYDVLESQ KGIGMNEPLV DCEGYPRSDV DLYQVRTARH NIICLQNDHK AVMKQVEEAL HQLHARDKEK QARDMAEAHK EAMSRKLGQS ESQGPPRAFA KVNSISPGSP ASIAGLQVDD EIVEFGSVNT QNFQSLHNIG SVVQHSEGKP LNVTVIRRGE KHQLRLVPTR WAGKGLLGCN IIPLQR.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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PSMD9

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