PSMB3

Alternative Names: Proteasome chain 13, Proteasome component C10-II, Proteasome theta chain, Proteasome (prosome, macropain) subunit beta type 3, HC10-II, EC 3.4.25.1, MGC4147.

The proteasome is an organized proteinase complex with a ring-shaped 20S core structure made up of four rings of 28 non-identical subunits. These subunits are divided into 7 alpha subunits and 7 beta subunits in each ring. Proteasomes are abundant in eukaryotic cells and are responsible for cleaving peptides in a non-lysosomal pathway that is dependent on ATP and ubiquitin. The immunoproteasome, a modified form of the proteasome, plays a key role in processing class I MHC peptides.

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  • Sku: PSB-enz-200-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human Proteasome Subunit Beta Type 3 is a protein that belongs to the proteasome subunit beta family. This protein plays a critical role in the degradation of intracellular proteins, regulating various cellular processes. With a molecular weight of approximately 26 kDa, Recombinant Human Proteasome Subunit Beta Type 3 is essential for maintaining protein homeostasis within the cell.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
25.1 kDa
Structure Heteromer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation PSMB3 protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 200mM NaCl, 1mM DTT and 50% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MSIMSYNGGA VMAMKGKNCV AIAADRRFGI QAQMVTTDFQ KIFPMGDRLY IGLAGLATDV QTVAQRLKFR LNLYELKEGR QIKPYTLMSM VANLLYEKRF GPYYTEPVIA GLDPKTFKPF ICSLDLIGCP MVTDDFVVSG TCAEQMYGMC ESLWEPNMDP DHLFETISQA MLNAVDRDAV SGMGVIVHII EKDKITTRTL KARMD

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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PSMB3

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