PSIP1

Alternative Names: PC4 and SFRS1 Interacting Protein 1, PC4 And SFRS1 Interacting Protein 2, Lens Epithelium-Derived Growth Factor, Transcriptional Coactivator P75/P52, Transcriptional Coactivator P52/P75, Dense Fine Speckles 70 KDa Protein, CLL-Associated Antigen KW-7, DFS 70, PSIP1, DFS70, LEDGF, PAIP, P52, P75

PSIP1, also known as PC4 and SFRS1 Interacting Protein 1, is a transcriptional coactivator that plays a crucial role in the differentiation and neurogenesis of neuroepithelial stem cells. It is also involved in regulating gene expression in lens epithelial cells and in responding to stress. Moreover, PSIP1 is important in the final differentiation of lens epithelial cells into fiber cells. Additionally, it acts as a protective factor during stress-induced apoptosis. Furthermore, PSIP1 serves as a cellular cofactor for the integration of lentiviral DNA.

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  • Sku: PSB-pro-2267-50µg
  • Vendor: ProSpec-Tany
$600.00 USD
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Title

Product Details

Product Description

Recombinant Human PC4 And SFRS1 Interacting Protein 1 (PSIP1) is a protein that interacts with PC4 and SFRS1, playing a significant role in various cellular processes. Belonging to the PSIP1 family, this protein is involved in transcriptional regulation, DNA repair, and chromatin organization. With a molecular weight of approximately X kDa, PSIP1 functions as a bridge between transcription factors and the transcriptional machinery, facilitating the assembly of transcriptional complexes. Its intricate involvement in these fundamental cellular mechanisms highlights the importance of understanding the functional significance of PSIP1 in various biological processes.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System Sf9 - Insect cells
Purity 95.0 % by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation PSIP1 is supplied in20mM HEPES buffer pH-8.0, 200mM NaCl and 20% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

Check Uniprot Link

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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PSIP1

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