PSG5

Alternative Names: Pregnancy-Specific Beta-1 Glycoprotein, Pregnancy-Specific Beta-1-Glycoprotein 5, Pregnancy-Specific Beta-1-Glycoprotein 5, Pregnancy-Specific Beta-1-Glycoprotein 5, Fetal Liver Non-Specific Cross-Reactive Antigen 3, FL-NCA-3, PS-beta-G-5, PSBG-5, PSG.

PSG5 is a member of the PSG family, a group of secreted glycoproteins highly expressed in fetal placental syncytiotrophoblast cells. PSGs can be detected in the serum as early as the first 2-3 weeks of pregnancy and their levels increase as the pregnancy progresses. At term, PSGs are the most abundant fetal protein found in maternal blood. PSG5 plays a crucial role in stimulating the secretion of TH2-type cytokines from monocytes and modulating the maternal immune system during pregnancy. This immune modulation helps protect the semi-allotypic fetus from rejection.

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  • Sku: PSB-pro-1633-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Safety Data Sheet
UniProt Listing
NCBI Link

Product Details

Product Description

Recombinant Human Pregnancy Specific Beta-1-Glycoprotein 5 (PSG5) is a protein that belongs to the pregnancy-specific glycoprotein (PSG) family. PSGs are secreted by the placenta during pregnancy and play a role in modulating the maternal immune system. PSG5 has a molecular weight of approximately X kDa and is involved in various biological processes related to pregnancy, including immunomodulation and fetal development. Understanding the functions and characteristics of PSG5 can provide valuable insights into the complex mechanisms underlying successful pregnancies.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System E. coli
Purity 80% by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 36.4 kDa
Structure Homodimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Frozen
Formulation The PSG5 solution contains 20mM Tris-HCl buffer (pH 8.0), 1M Urea and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSQVTIEAL PPKVSEGKDV LLLVHNLPQN LAGYIWYKGQ LMDLYHYITS YVVDGQINIY GPAYTGRETV YSNASLLIQN VTREDAGSYT LHIIKRGDRT RGVTGYFTFN LYLKLPKPYI TINNSKPREN KDVLAFTCEP KSENYTYIWW LNGQSLPVSP RVKRPIENRI LILPSVTRNE TGPYECEIRD RDGGMRSDPV TLNVLYGPDL PSIYPSFTYY RSGENLYLSC FAESNPPAEY FWTINGKFQQ SGQKLSIPQI TTKHRGLYTC SVRNSATGKE SSKSMTVEVS APSGIGRLPL LNPI

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution
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References

Not Available
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PSG5
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