PPP4C

Alternative Names: Not Available

Protein Phosphatase 4 Catalytic subunit (PPP4C) is a key component of the Serine/threonine-protein phosphatase catalytic subunits involved in dephosphorylation and regulation of HDAC3. The PPP holoenzyme is composed of a regulatory subunit, a variable subunit, and a catalytic subunit. The major families of protein phosphatase catalytic subunits are known as PP1, PP2A, PP2B (calcineurin), and PP2C.

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  • Sku: PSB-enz-266-5µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Protein Phosphatase 4 Catalytic subunit is a member of the protein phosphatase family, specifically belonging to the PP4 subfamily. This enzyme is responsible for the dephosphorylation of proteins, playing a crucial role in regulating various cellular processes. With a molecular weight of approximately 37 kDa, the Recombinant Human Protein Phosphatase 4 Catalytic subunit is widely used in research studies to elucidate its function and potential therapeutic applications.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
37.5 kDa
Structure Homotrimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The PPP4C solution (1mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSMAEISDL DRQIEQLRRC ELIKESEVKA LCAKAREILV EESNVQRVDS PVTVCGDIHG QFYDLKELFR VGGDVPETNY LFMGDFVDRG FYSVETFLLL LALKVRYPDR ITLIRGNHES RQITQVYGFY DECLRKYGSV TVWRYCTEIF DYLSLSAIID GKIFCVHGGL SPSIQTLDQI RTIDRKQEVP HDGPMCDLLW SDPEDTTGWG VSPRGAGYLF GSDVVAQFNA ANDIDMICRA HQLVMEGYKW HFNETVLTVW SAPNYCYRCG NVAAILELDE HLQKDFIIFE AAPQETRGIP SKKPVADYFL

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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PPP4C

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