PPP1R3B

Alternative Names: Protein Phosphatase 1, Regulatory Subunit 3B, Protein phosphatase 1 regulatory subunit 3B, Hepatic glycogen-targeting protein phosphatase 1 regulatory subunit GL, Protein phosphatase 1 regulatory subunit 4, PP1 subunit R4, Protein phosphatase 1 subunit GL, PTG, PPP1R4, PPP1R3B, Protein phosphatase 1 regulatory subunit GL.

Protein Phosphatase 1, Regulatory Subunit 3B (PPP1R3B) is an essential component of the protein phosphatase-1 enzyme in the body. It plays a significant role in regulating glycogen synthesis in the liver and skeletal muscle. PPP1R3B is implicated in type 2 diabetes and maturity-onset diabetes of the young.

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  • Sku: PSB-pro-1700-5µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Protein Phosphatase 1, Regulatory Subunit 3B (PPP1R3B) is a regulatory subunit of protein phosphatase 1 (PP1), a critical enzyme involved in the dephosphorylation of various cellular proteins. PPP1R3B belongs to the PPP1R3 family and plays a crucial role in glycogen metabolism by regulating glycogen synthase and glycogen phosphorylase activities. With a molecular weight of approximately X kDa, PPP1R3B acts as a scaffold protein, facilitating the interaction between PP1 and glycogen-associated enzymes, thereby modulating glycogen synthesis and breakdown pathways.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 85.0% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The PPP1R3B solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M urea and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSMMAVDIE YRYNCMAPSL RQERFAFKIS PKPSKPLRPC IQLSSKNEAS GMVAPAVQEK KVKKRVSFAD NQGLALTMVK VFSEFDDPLD MPFNITELLD NIVSLTTAES ESFVLDFSQP SADYLDFRNR LQADHVCLEN CVLKDKAIAG TVKVQNLAFE KTVKIRMTFD TWKSYTDFPC QYVKDTYAGS DRDTFSFDIS LPEKIQSYER MEFAVYYECN GQTYWDSNRG KNYRIIRAEL KSTQGMTKPH SGPDLGISFD QFGSPRCSYG LFPEWPSYLG YEKLGPYY.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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PPP1R3B

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