POU6F1

Alternative Names: BRN5, Brain-5, Brn-5, TCFB1, MPOU, mPOU homeobox protein, Brain-specific homeobox/POU domain protein 5.

POU6F1 is a transcription factor belonging to the POU transcription factor family. It preferentially binds to a variant of the octamer motif (5'-ATGATAAT-3'). While POU6F1 is only expressed in the embryo during brain development, its expression is limited to the brain, heart, skeletal muscle, and lung in adult individuals. In the brain, POU6F1 shows the highest levels of expression in specific cell layers of the cortex, olfactory bulb, hippocampus, and cerebellum.

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  • Sku: PSB-pro-1484-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human POU Class 6 Homeobox 1, also known as POU6F1, is a protein belonging to the POU domain family. With a molecular weight of approximately X kDa, this protein plays a significant role in the regulation of gene expression and development. It acts as a transcription factor, binding to specific DNA sequences, and is involved in the differentiation and maintenance of neuronal cells. Understanding the functions and mechanisms of Recombinant Human POU Class 6 Homeobox 1 is crucial for unraveling the complexities of neurodevelopmental processes.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 85.0% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The POU5F1 solution contains 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSMPGISSQ ILTNAQGQVI GTLPWVVNSA SVAAPAPAQS LQVQAVTPQL LLNAQGQVIA TLASSPLPPP VAVRKPSTPE SPAKSEVQPI QPTPTVPQPA VVIASPAPAA KPSASAPIPI TCSETPTVSQ LVSKPHTPSL DEDGINLEEI REFAKNFKIR RLSLGLTQTQ VGQALTATEG PAYSQSAICR FEKLDITPKS AQKLKPVLEK WLNEAELRNQ EGQQNLMEFV GGEPSKKRKR RTSFTPQAIE ALNAYFEKNP LPTGQEITEI AKELNYDREV VRVWFCNRRQ TLKNTSKLNV FQIP.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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POU6F1

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