POLR2D

Alternative Names: HSRPB4, HSRBP4, RBP4, RPB16, RNA polymerase II subunit B4, DNA-directed RNA polymerase II subunit RPB4, DNA-directed RNA polymerase II subunit D, RNA polymerase II 16 kDa subunit, POLR2D.

Recombinant Human Polymerase II Polypeptide D is a member of the DNA polymerase family, specifically belonging to the RNA polymerase subfamily. With a molecular weight of approximately 180 kDa, this enzyme plays a critical role in the transcription process by catalyzing the synthesis of RNA from a DNA template. Recombinant Human Polymerase II Polypeptide D is a key component of the RNA polymerase II complex, which is essential for gene expression and regulation in eukaryotic organisms.

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  • Sku: PSB-enz-739-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human Polymerase II Polypeptide D is a member of the DNA polymerase family, specifically belonging to the RNA polymerase subfamily. With a molecular weight of approximately 180 kDa, this enzyme plays a critical role in the transcription process by catalyzing the synthesis of RNA from a DNA template. Recombinant Human Polymerase II Polypeptide D is a key component of the RNA polymerase II complex, which is essential for gene expression and regulation in eukaryotic organisms.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
18.7 kDa
Structure Dimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The POLR2D solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSMAAGGSD PRAGDVEEDA SQLIFPKEFE TAETLLNSEV HMLLEHRKQQ NESAEDEQEL SEVFMKTLNY TARFSRFKNR ETIASVRSLL LQKKLHKFEL ACLANLCPET AEESKALIPS LEGRFEDEEL QQILDDIQTK RSFQY.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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POLR2D

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