PNC-27

Alternative Names: Not Available

PNC-27 is a synthetic peptide derived from the protein p53, which belongs to the tumor suppressor family. This peptide has a molecular weight of approximately 3.5 kDa. PNC-27 has gained attention in cancer research due to its potential anticancer properties and ability to induce apoptosis in cancer cells. Its mechanism of action involves disrupting the mitochondrial membrane, leading to the release of cytochrome c and subsequent activation of caspases. PNC-27 has shown promise as a potential therapeutic agent in preclinical studies, warranting further investigation for its potential clinical applications in cancer treatment.

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  • Sku: PSB-hor-038-5mg
  • Vendor: ProSpec-Tany
$200.00 USD
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Title

Product Details

Product Description

PNC-27 is a synthetic peptide derived from the protein p53, which belongs to the tumor suppressor family. This peptide has a molecular weight of approximately 3.5 kDa. PNC-27 has gained attention in cancer research due to its potential anticancer properties and ability to induce apoptosis in cancer cells. Its mechanism of action involves disrupting the mitochondrial membrane, leading to the release of cytochrome c and subsequent activation of caspases. PNC-27 has shown promise as a potential therapeutic agent in preclinical studies, warranting further investigation for its potential clinical applications in cancer treatment.

Current Lead Time

7-14 Days

Product Specifications

Species
Contact for Details
Expression System Contact for Details
Purity 97.0 % by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) No
Molecular Weight
N/A
Structure Dimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Lyophilized
Formulation The protein was lyophilized with no additives.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

H-Pro-Pro-Leu-Ser-Gln-Glu-Thr-Phe-Ser-Asp-Leu-Trp-Lys-Leu-Leu-Lys-Lys-Trp-Lys-Met-Arg-Arg-Asn-Gln-Phe-Trp-Val-Lys-Val-Gln-Arg-Gly-OH

Storage Instruction

Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C. Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized C-Peptide in sterile 18MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available

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PNC-27

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