pIP10

Alternative Names: CRG-2, CXCL10.

CXCL10 is a small cytokine in the CXC chemokine family. It is produced by various cell types, such as monocytes, endothelial cells, and fibroblasts. CXCL10 plays a role in chemoattraction for monocytes and T cells, promoting T cell adhesion to endothelial cells, antitumor activity, and inhibiting bone marrow colony formation and angiogenesis. The gene for CXCL10 is located on human chromosome 4 in a cluster with other CXC chemokines. Its effects are mediated through binding to the cell surface chemokine receptor CXCR3. The three-dimensional crystal structure of CXCL10 has been resolved under three different conditions with a resolution up to 1.92A.

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  • Sku: PSB-chm-046-10µg
  • Vendor: ProSpec-Tany
$130.00 USD
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Title

Product Details

Product Description

Recombinant Guinea Pig IP-10 (CXCL10) is a chemokine belonging to the CXC subfamily. With a molecular weight of approximately 8.5 kDa, this protein plays a key role in immune responses by attracting and activating T cells, monocytes, and natural killer cells. Recombinant Guinea Pig IP-10 is commonly used in research to study inflammation, autoimmune diseases, and cancer.

Current Lead Time

7-14 Days

Product Specifications

Species
Guinea Pig
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Dimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Lyophilized
Formulation Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM Sodium Phosphate, pH 7.5.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

IPHSRTIRCT CIETSTQPVN PKSFKKLEII PASQSCPRVE IIATMKMNGE KRCLDPESKV IKNLLKAVRK ERSKRS

Storage Instruction

Lyophilized IP10 although stable at room temperature for 3 weeks, should be stored desiccated below -18° C. Upon reconstitution IP10 Human should be stored at 4° C between 2-7 days and for future use below -18° C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized IP10 in sterile water at a concentration of 0.1 mg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available

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pIP10

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