pIL 8

Alternative Names: Monocyte-derived neutrophil chemotactic factor, MDNCF, Monocyte-derived neutrophil-activating peptide, MONAP, Neutrophil-activating protein 1, NAP-1, Granulocyte chemotactic protein 1, GCP-1, T-cell chemotactic factor, Emoctakin, K60, NAF, LECT, LUCT, Protein 3-10C, 3-10C, LYNAP, SCYB8, IL-8, CXCL8, TSG-1, AMCF-I, b-ENAP, Alveolar macrophage chemotactic factor I.

IL-8 is a chemokine released by various cell types, including macrophages and endothelial cells. It is stored in Weibel-Palade bodies of endothelial cells. Macrophages release IL-8 when encountering antigens, which attracts neutrophils to the site of inflammation.

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  • Sku: PSB-chm-340-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Safety Data Sheet
UniProt Listing
NCBI Link

Product Details

Product Description

Recombinant Porcine Interleukin-8 (1-72) (CXCL8) is a chemokine protein that belongs to the CXC chemokine family. With a molecular weight of approximately 8.3 kDa, CXCL8 plays a key role in the regulation of immune responses and inflammation. This recombinant protein is commonly used in research studies to investigate the signaling pathways involved in chemotaxis and leukocyte recruitment.

Current Lead Time

7-14 Days

Product Specifications

Species
 Pig
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
 The biological activity was determined by a chemotaxis bioassay using human peripheral blood neutrophils is in a concentration range of 20-200 ng/ml. The biological activity was determined by a chemotaxis bioassay using human peripheral blood neutrophils is in a concentration range of 20-200 ng/ml.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 N/A
Structure Homodimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Lyophilized
Formulation Lyophilized from a 0.2µm filtered concentrated solution in 1×PBS, pH 7.4.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

ARVSAELRCQ CINTHSTPFH PKFIKELRVI ESGPHCENSE IIVKLVNGKE VCLDPKEKWV QKVVQIFLKR TEKQQQQQ.

Storage Instruction

Lyophilized Interleukin-8 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CXCL8 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized Interleukin 8 in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available
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pIL 8
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