PF4 Variant-1

Alternative Names: CXCL4, PF-4, PF4, Iroplact, Oncostatin-A, SCYB4, MGC138298

Platelet factor-4 is a 70 amino acid protein released from activated platelets that neutralizes molecules on blood vessel surfaces, inhibiting antithrombin III activity and promoting coagulation. It also acts as a chemoattractant for neutrophils and fibroblasts, suggesting a role in inflammation and wound repair. PF4 is used for diagnosing induced thrombocytopenia and as an inhibitor in tumor therapy to prevent angiogenesis. On the other hand, Oncostatin-A is a member of the CXC chemokine family.

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  • Sku: PSB-chm-243-1µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human Platelet Factor-4 (CXCL4V1) Variant-1 is a member of the CXC chemokine family, known for its role in regulating inflammation and immune responses. This protein has a molecular weight of approximately 8.3 kDa and is involved in the recruitment and activation of immune cells at sites of injury or infection. Recombinant Human Platelet Factor-4 (CXCL4V1) Variant-1 is commonly used in research and therapeutic applications to study its effects on immune cell function and inflammatory processes.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Dimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Lyophilized
Formulation The protein was lyophilized without additives.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MHHHHHHEAE EDGDLQCLCV KTTSQVRPRH ITSLEVIKAG PHCPTAQLIA TLKNGRKICL DLQALLYKKI IKEHLES.

Storage Instruction

Human CXCL4 although stable at 25°C 1 week, should be stored desiccated below -18°C. Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized CXCL4 in sterile 18MΩ-cm H₂O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available

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PF4 Variant-1

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