PF4

Alternative Names: Iroplact, MGC138298, Oncostatin-A, PF-4, PF4, SCYB4, CXCL4

Platelet factor-4 is a protein released from activated platelets that plays a key role in inhibiting antithrombin III activity on blood vessel walls, promoting coagulation. It also acts as a chemoattractant for neutrophils and fibroblasts, suggesting a role in inflammation and wound healing. Oncostatin-A is a member of the CXC chemokine family and is used as an inhibitor of angiogenesis in tumor therapy.

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  • Sku: PSB-chm-350-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human Platelet Factor-4 (CXCL4) is a chemokine protein belonging to the CXC chemokine family. With a molecular weight of approximately 7.8 kDa, CXCL4 plays a role in inflammation and immune response regulation. As a member of the CXC chemokine family, CXCL4 is involved in the recruitment and activation of immune cells at sites of injury or infection. Its ability to modulate immune cell function makes it a valuable tool for research in various disease models.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 97.0 % by SDS-PAGE
Activity
The biological activity determined by a chemotaxis bioassay using human fibroblasts is in a concentration of 1.0-10 ng/ml.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Dimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Lyophilized
Formulation The CXCL4 protein was filtered (0.2µm) and lyophilized from a concentrated solution containing 20mM PB and 1.5M NaCl, pH 7.4.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

EAEEDGDLQC LCVKTTSQVR PRHITSLEVI KAGPHCPTAQ LIATLKNGRK ICLDLQAPLY

Storage Instruction

Lyophilized CXCL4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CXCL4 should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized CXCL4 in sterile 18MΩ-cm H₂O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available

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PF4

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