PCMT1

Alternative Names: EC 2.1.1.77, PIMT, PCMT1, Protein L-isoaspartyl/D-aspartyl methyltransferase, Protein-beta-aspartate methyltransferase, L-isoaspartyl protein carboxyl methyltransferase.

Recombinant Human Protein-L-Isoaspartate O-Methyltransferase is an enzyme that plays a role in repairing damaged proteins by catalyzing the transfer of a methyl group to isoaspartyl residues. Belonging to the O-methyltransferase family, this enzyme is crucial for maintaining protein integrity and stability. With a molecular weight of approximately 30 kDa, Recombinant Human Protein-L-Isoaspartate O-Methyltransferase is a key player in the prevention of protein misfolding and aggregation.

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  • Sku: PSB-enz-522-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human Protein-L-Isoaspartate O-Methyltransferase is an enzyme that plays a role in repairing damaged proteins by catalyzing the transfer of a methyl group to isoaspartyl residues. Belonging to the O-methyltransferase family, this enzyme is crucial for maintaining protein integrity and stability. With a molecular weight of approximately 30 kDa, Recombinant Human Protein-L-Isoaspartate O-Methyltransferase is a key player in the prevention of protein misfolding and aggregation.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation PCMT1 Human solution containing 20mM Tris-HCl pH-8, 0.1M NaCl, & 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

RGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMAWK SGGASHSELI HNLRKNGIIK TDKVFEVMLA TDRSHYAKCN PYMDSPQSIG FQATISAPHM HAYALELLFD QLHEGAKALD VGSGSGILTA CFARMVGCTG KVIGIDHIKE LVDDSINNVR KDDPTLLSSG RVQLVVGDGR MGYAEEAPYD AIHVGAAAPV VPQALIDQLK PGGRLILPVG PAGGNQMLEQ YDKLQDGSIK MKPLMGVIYV PLTDKEKQWS RWK.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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PCMT1

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