Product Description

The Recombinant Ovine Leptin Triple Antagonist, Pegylated, is a synthetic protein designed to inhibit the activity of leptin, a hormone involved in regulating appetite and energy balance. Belonging to the family of recombinant proteins, this antagonist is created through genetic engineering techniques. With a weight of approximately X kDa (kilodaltons), it exerts its effects by binding to leptin receptors and blocking their activation. This Pegylated variant is modified with polyethylene glycol, which enhances its stability and prolongs its half-life in the body. By modulating leptin signaling, this antagonist holds potential in the field of obesity research and therapeutic interventions.

Current Lead Time

7-14 Days

Product Specifications

*For Research Use Only

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Lyophilized Leptin Antagonist Triple Mutant Ovine Recombinant although stable at room temperature for several weeks, should be stored desiccated below -18C. Upon reconstitution at > 0.1 Lep-tA mutant mg/ml and up to 2mM and filter sterilization Leptin mutant can be stored at 4C or even room temperature for several weeks making it suitable for long term infusion studies using osmotic pumps. At lower concentration addition of a carrier protein (0.1% HSA or BSA) is suggested.
Please prevent freeze-thaw cycles.

It is recommended to reconstitute the lyophilized Leptin-Antagonist Triple Mutant Ovine Recombinant in sterile water or sterile 0.4% NaHCO3 adjusted to pH 8, not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Not Available