NUDT4

Alternative Names: Diphosphoinositol polyphosphate phosphohydrolase 2, DIPP-2, DIPP2, DIPP2alpha, DIPP2beta, Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 2, Nucleoside diphosphate-linked moiety X motif 4, NUDT4, KIAA0487, HDCMB47P, EC 3.6.1.52.

NUDT4 controls the breakdown of diphosphoinositol polyphosphates, molecules with high energy that can regulate cellular processes such as intracellular trafficking.

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  • Sku: PSB-enz-708-2µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Nudix Type Motif 4 is a protein belonging to the Nudix hydrolase family, which is involved in the hydrolysis of nucleoside diphosphate linked to another moiety. It is a crucial enzyme in maintaining cellular homeostasis by catalyzing the breakdown of potentially harmful nucleotide derivatives. This protein has a molecular weight of approximately 18 kDa and plays a significant role in nucleotide metabolism within the cell.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
22.7 kDa
Structure Dimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation NUDT4 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 10% glycerol and 0.1M NaCl.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSMMKFKPN QTRTYDREGF KKRAACLCFR SEQEDEVLLV SSSRYPDQWI VPGGGMEPEE EPGGAAVREV YEEAGVKGKL GRLLGIFENQ DRKHRTYVYV LTVTEILEDW EDSVNIGRKR EWFKVEDAIK VLQCHKPVHA EYLEKLKLGC SPANGNSTVP SLPDNNALFV TAAQTSGLPS SVR.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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NUDT4

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