NMNAT2

Alternative Names: Not Available

Recombinant Human Nicotinamide Nucleotide Adenylyltransferase 2, also known as NMNAT2, is a member of the nicotinamide/nicotinate mononucleotide adenylyltransferase family. This enzyme plays a key role in the biosynthesis of NAD+, a critical coenzyme involved in various cellular processes. NMNAT2 has a molecular weight of approximately 33 kDa and is essential for maintaining cellular homeostasis through its involvement in NAD+ metabolism. Its recombinant form is commonly used in research and pharmaceutical applications for studying the role of NAD+ in aging, neurodegenerative diseases, and metabolic disorders.

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  • Sku: PSB-enz-509-2µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Nicotinamide Nucleotide Adenylyltransferase 2, also known as NMNAT2, is a member of the nicotinamide/nicotinate mononucleotide adenylyltransferase family. This enzyme plays a key role in the biosynthesis of NAD+, a critical coenzyme involved in various cellular processes. NMNAT2 has a molecular weight of approximately 33 kDa and is essential for maintaining cellular homeostasis through its involvement in NAD+ metabolism. Its recombinant form is commonly used in research and pharmaceutical applications for studying the role of NAD+ in aging, neurodegenerative diseases, and metabolic disorders.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 85.0% by SDS-PAGE
Activity
Specific activity: > 500 pmol/min/ug. One unit will convert 1.0 pmole of beta-NADH per minute to beta-NAD at PH 8.0 at 37°C.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
36.6 kDa
Structure Dimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation NMNAT2 protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 20% glycerol and 1mM DTT.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MTETTKTHVI LLACGSFNPI TKGHIQMFER ARDYLHKTGR FIVIGGIVSP VHDSYGKQGL VSSRHRLIMC QLAVQNSDWI RVDPWECYQD TWQTTCSVLE HHRDLMKRVT GCILSNVNTP SMTPVIGQPQ NETPQPIYQN SNVATKPTAA KILGKVGESL SRICCVRPPV ERFTFVDENA NLGTVMRYEE IELRILLLCG SDLLESFCIP GLWNEADMEV IVGDFGIVVV PRDAADTDRI MNHSSILRKY KNNIMVVKDD INHPMSVVSS TKSRLALQHG DGHVVDYLSQ PVIDYILKSQ LYINASG

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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NMNAT2

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