NMI

Alternative Names: "N-myc Interactor (and STAT)."

N-myc-interactor (NMI) is a member of the Myc oncogene family and plays a crucial role in cell proliferation, differentiation, and neoplastic transformation. NMI collaborates with all STATs, except STAT2, and enhances STAT-mediated transcription following exposure to IL2 and IFN-gamma cytokines. Although NMI mRNA is expressed in tissues of human fetuses and adults, it is found in low abundance in the brain but is present in high quantities in cancer cell lines, particularly myeloid leukemias.

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  • Sku: PSB-pro-070-5µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human N-Myc Interactor (NMI) is a protein that belongs to the N-Myc Interactor family. With a molecular weight of approximately X kDa, NMI plays a significant role in various cellular processes. This protein is involved in transcriptional regulation, signal transduction, and protein-protein interactions. Understanding the functions and mechanisms of NMI can provide valuable insights into its potential implications in disease pathogenesis and therapeutic interventions.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
Activity Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
37.2 kDa
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The NMI protein solution (0.5mg/1ml) is formulated in 20mM Tris-HCl buffer (pH8.0)1mM DTT and 20% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MEADKDDTQQ ILKEHSPDEF IKDEQNKGLI DEITKKNIQLK KEIQKLETE LQEATKEFQI KEDIPETKMK FLSVETPEND SQLSNISCSF QVSSKVPYEI QKGQALITFE KEEVAQNVVS MSKHHVQIKDV NLEVTAKPV PLNSGVRFQV YVEVSKMKIN VTEIPDTLRE DQMRDKLELS FSKSRNGGGE VDRVDYDRQS GSAVITFVEI GVADKILKKKEYPLYINQTC HRVTVSPYTE IHLKKYQIFS GTSKRTVLLT GMEGIQMDEE IVEDLINIHF QRAKNGGGEV DVVKCSLGQP HIAYFEE

Storage Instruction

Store at 4° C if entire vial will be used within 2-4 weeks. Store, frozen at -20° C for longer periods of time. Please avoid freeze thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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NMI

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