NME4

Alternative Names: CDH1, Cadherin-1, Cadherin-E, CD324, CD324 antigen, CDHE, E-cadherin, ECAD, Epithelial cadherin, Uvomorulin, UVO, LCAM, CAM 120/80, Arc-1

E-cadherin (uvomorulin, cell-CAM120/80) is a calcium-dependent cell adhesion molecule found mainly in epithelial tissues. It plays a crucial role in cell growth and development by regulating tissue architecture and maintaining tissue integrity. Studies have consistently shown that decreased or absent E-cadherin expression in carcinomas is associated with increased invasion and metastasis potential.

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  • Sku: PSB-pro-219-5µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Non-Metastatic Cells 4, commonly referred to as RHNM4, is a specialized cell line that belongs to the family of non-metastatic cells. These cells are extensively used in scientific research and drug development studies to investigate the mechanisms underlying tumor metastasis. RHNM4 cells have a well-defined weight, although it may vary depending on the specific experimental conditions. This cell line is of great interest to researchers due to its unique characteristics and potential insights it can provide into the complex process of metastasis.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System HEK 293
Purity 95% by SDS-PAGE
Activity
Activity Not Available
Activity Assay
Animal Component Free (ACF) No
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Lyophilized
Formulation The CDH1 protein was lyophilized from a 0.2µm filtered solution in PBS, pH7.4. The CDH1 protein was lyophilized from a 0.2µm filtered solution in PBS, pH7.4.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

DWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIHHHHHH.

Storage Instruction

Lyophilized E-Cadherin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CDH1 should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized CDH1 in sterile 18M-cm H₂O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available

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NME4

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