NDUFS4

Alternative Names: NADH dehydrogenase [ubiquinone] iron-sulfur protein 4 mitochondrial, NDUFS4, NADH-ubiquinone oxidoreductase 18 kDa subunit, Complex I-18 kDa, CI-18 kDa, Complex I-AQDQ, CI-AQDQ, AQDQ

NDUFS4 is a crucial subunit of Complex I, the main enzyme complex in the mitochondrial respiratory chain responsible for producing ATP, the primary energy source for cells. NDUFS4 plays a key role in transferring electrons from NADH to ubiquinone through a series of redox centers. Mutations in NDUFS4 are common and can disrupt the assembly of Complex I, impacting cellular ATP production.

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  • Sku: PSB-enz-421-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human Histidine NADH Dehydrogenase Fe-S Protein 4 is a member of the NADH dehydrogenase (ubiquinone) iron-sulfur protein family. This protein plays a significant role in the mitochondrial electron transport chain, specifically in the transfer of electrons from NADH to ubiquinone. With a molecular weight of approximately 24 kDa, Recombinant Human Histidine NADH Dehydrogenase Fe-S Protein 4 is essential in maintaining cellular energy production through oxidative phosphorylation.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The NDUFS4 solution contains 20mM Tris pH-8 & 30% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MAQDQTQDTQ LITVDEKLDI TTLTGVPEEH IKTRKVRIFV PARNNMQSGV NNTKKWKMEF DTRERWENPL MGWASTADPL SNMVLTFSTK EDAVSFAEKN GWSYDIEERK VPKPKSKSYG ANFSWNKRTR VSTK.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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NDUFS4

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