NAP 2

Alternative Names: Platelet basic protein, PBP, pro-platelet basic protein (chemokine (C-X-C motif) ligand 7), CXCL7, Small inducible cytokine B7, SCYB7, Leukocyte-derived growth factor, LDGF, Macrophage-derived growth factor, MDGF, TC1, TC2, TGB, TGB1, B-TG1, Beta-TG, CTAP3, CTAPIII, CTAP-III, NAP-2, THBGB, THBGB1, LA-PF4.

CXCL7 is a small cytokine from the CXC chemokine family that is released in high levels from activated platelets. It has various effects on processes such as mitogenesis, synthesis of extracellular matrix, glucose metabolism, and synthesis of plasminogen activator.

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  • Sku: PSB-chm-274-2µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Safety Data Sheet
UniProt Listing
NCBI Link

Product Details

Product Description

Recombinant Human Neutrophil Activating Protein-2 (CXCL7) is a chemokine belonging to the CXC subfamily. It plays a key role in immune response by activating neutrophils and promoting their migration to sites of inflammation. CXCL7 has a molecular weight of approximately 7.8 kDa, making it a small protein with potent biological activity. This chemokine is involved in the regulation of inflammatory processes and is a valuable tool for studying immune responses in various experimental models.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System E. coli
Purity 97 % by SDS-PAGE
Activity
 The specific activity as determined by the ability of NAP2 to chemoattract human neurotrophils using a concentration of 1-10ng/ml corresponding to a Specific Activity of 100,000-1,000,000IU/mg. The specific activity as determined by the ability of NAP2 to chemoattract human neurotrophils using a concentration of 1-10ng/ml corresponding to a Specific Activity of 100,000-1,000,000IU/mg.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 N/A
Structure Homodimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Lyophilized
Formulation The CXCL7 protein was lyophilized from a concentrated (1mg/ml) sterile solution containing no additives.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

The sequence of the first five N-terminal amino acids was determined and was found to be Ala-Glu-Leu-Arg-Cys.

Storage Instruction

Lyophilized NAP-2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CXCL7should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized Neutrophil Activating Protein-2in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available
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NAP 2
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