mTECK

Alternative Names: Thymus-expressed chemokine, Chemokine TECK, CCL25, SCYA25, Small-inducible cytokine A25, C-C motif chemokine 25, TECK, Ckb15, MGC150327.

CCL25, also known as Teck, is a novel CC chemokine with genetic similarities to other chemokines. It is mainly expressed in the thymus and small intestine, with dendritic cells in the thymus producing the protein. CCL25 signals through the CCR9 receptor and may play a role in T-cell development. Recombinant human and mouse Teck have been shown to attract activated macrophages, dendritic cells, and thymocytes, as well as thymocytes, macrophages, THP-1 cells, and dendritic cells. However, the protein does not have chemotactic activity on peripheral blood lymphocytes or neutrophils.

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  • Sku: PSB-chm-259-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Safety Data Sheet
UniProt Listing
NCBI Link

Product Details

Product Description

Recombinant Mouse Thymus Expressed Chemokine (CCL25) is a chemokine protein belonging to the CC chemokine family. It plays a role in immune response by regulating the migration and activation of various immune cells. CCL25 has a molecular weight of approximately 8.5 kDa and is primarily expressed in the thymus, where it helps in the development and maturation of T cells. This chemokine is involved in the homing of T cells to the thymus and plays a crucial role in maintaining immune homeostasis.

Current Lead Time

7-14 Days

Product Specifications

Species
 Mouse
Expression System E. coli
Purity 97.0% by SDS-PAGE
Activity
 Determined by its ability to chemoattract human CCR9 transfected BaF3 mouse pro-B cells using a concentration range of 0.1-0.5 ug/ml. Determined by its ability to chemoattract human CCR9 transfected BaF3 mouse pro-B cells using a concentration range of 0.1-0.5 ug/ml.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 14.1 kDa
Structure Dimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Lyophilized
Formulation Filtered (0.2µm) and lyophilized from a concentrated (1mg/ml) solution in in 1×PBS, pH7.4.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

QGAFEDCCLG YQHRIKWNVL RHARNYHQQE VSGSCNLRAV RFYFRQKVVC GNPEDMNVKR AIRILTARKR LVHWKSASDS QTERKKSNHM KSKVENPNST SVRSATLGHP RMVMMPRKTN N

Storage Instruction

Lyophilized TECK although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution TECK should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized TECK in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available
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mTECK
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