MSRB3

Alternative Names: MSRB3, Methionine-R-sulfoxide reductase B3, DFNB74, FLJ36866, DKFZp686C1178

MSRB3 is a protein that belongs to the MSR family and is responsible for converting methionine sulfoxide to methionine. Acting as a monomer, the MSRB3 enzyme relies on zinc as a cofactor. Its main role is to protect against oxidative damage caused by reactive oxygen species in organs, such as the skin. Additionally, MSRB3 plays a crucial role in cold tolerance by reducing MetO and ROS accumulation in the endoplasmic reticulum during cold acclimation.

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  • Sku: PSB-enz-093-2µg
  • Vendor: ProSpec-Tany
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Safety Data Sheet
UniProt Listing
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Product Details

Product Description

Recombinant Human Methionine Sulfoxide Reductase B3 is a member of the methionine sulfoxide reductase family, responsible for reducing methionine sulfoxide residues to methionine in proteins. This enzyme plays a crucial role in protecting cells from oxidative damage by repairing oxidized proteins. Recombinant Human Methionine Sulfoxide Reductase B3 has a molecular weight of approximately 19 kDa and is commonly used in research studies to investigate its role in cellular function and oxidative stress response.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 N/A
Structure Monomer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Frozen
Formulation The MSRB3 solution (1 mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 10% glycerol and 0.1mM PMSF.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MCGLPSGSCR DKKNCKVVFS QQELRKRLTP LQYHVTQEKG TESAFEGEYT HHKDPGIYKC VVCGTPLFKS ETKFDSGSGW PSFHDVINSE AITFTDDFSY GMHRVETSCS QCGAHLGHIF DDGPRPTGKR YCINSAALSF TPADSSGTAE GGSGVASPAQ ADKAELLEHH HHHH.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution
​

References

Not Available
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MSRB3
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