mS100A5

Alternative Names: Protein S100-A5, Protein S-100D, S100 calcium-binding protein A5, S100a5, S100D, S100D9.

S100A5 is a member of the S100 protein family, characterized by its possession of 2 EF-hand calcium-binding motifs. These proteins are found in the cytoplasm and/or nucleus of various cells and play a role in regulating cellular processes such as cell cycle progression and differentiation. Notably, S100A5 has a much higher affinity for calcium ions (Ca2+) compared to other S100 proteins tested in the same experimental conditions, ranging from 20 to 100 fold. Additionally, S100A5 can also bind zinc ions (Zn2+) and copper ions (Cu2+), with copper ions having a strong detrimental effect on the binding of calcium ions. Expression of S100A5 is limited to specific regions in the adult brain.

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  • Sku: PSB-pro-1084-5µg
  • Vendor: ProSpec-Tany
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Safety Data Sheet
UniProt Listing
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Product Details

Product Description

Recombinant Mouse S100 Calcium Binding Protein A5, also known as S100A5, is a member of the S100 family of calcium-binding proteins. With a molecular weight of approximately 10.5 kDa, this protein plays a role in various cellular processes by binding to calcium ions. S100A5 is involved in the regulation of cell growth, differentiation, and apoptosis, making it a significant player in cellular signaling pathways. Its calcium-binding properties enable S100A5 to interact with target proteins, modulating their functions and contributing to the overall regulation of cellular activities.

Current Lead Time

7-14 Days

Product Specifications

Species
 Mouse
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 13.4 kDa
Structure Homodimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Frozen
Formulation S100A5 protein (1mg/ml) is supplied in 20mM Tris-HCl buffer, pH8.0, 40% glycerol, 3mM DTT and 200mM NaCl.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSHMETPLE KALTTMVTTF HKYSGREGSK LTLSRKELKE LIKTELSLAE KMKESSIDNL MKSLDKNSDQ EIDFKEYSVF LTTLCMAYND FFLEDNK.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution
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References

Not Available
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mS100A5
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