MMP23B

Alternative Names: EC 3.4.24.-, Femalysin, Matrix Metalloproteinase In The Female Reproductive Tract, MIFR, MIFR-1, Matrix Metalloproteinase-21, MMP-21, Matrix Metalloproteinase-22, MMP22, Matrix Metalloproteinase-23, MMP23, Matrix Metallopeptidase 23B, MMP23B, Matrix Metalloproteinase 22, MMP22, Matrix Metalloproteinase-23B, MMP23B, MMP23A, MMP-22, MMP-21.

MMP23B is a protease that belongs to the matrix metalloproteinase family and is located on chromosome 1p36.3. It plays a role in regulating the surface expression of certain potassium channels by retaining them in the endoplasmic reticulum. The MMP family members are responsible for breaking down the extracellular matrix during various physiological processes, including embryonic development, reproduction, tissue remodeling, and disease progression, such as arthritis and metastasis.

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  • Sku: PSB-enz-793-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Safety Data Sheet
UniProt Listing
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Product Details

Product Description

Recombinant Human Matrix Metallopeptidase 23B is a member of the matrix metalloproteinase (MMP) family, which are zinc-dependent endopeptidases involved in the breakdown of extracellular matrix components. This enzyme plays a role in tissue remodeling and is implicated in various physiological and pathological processes. Recombinant Human Matrix Metallopeptidase 23B has a molecular weight of approximately 55 kDa and is commonly used in research and drug development studies related to cancer, inflammation, and wound healing.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System E. coli
Purity 85.0% by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 22.6 kDa
Structure Homodimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Frozen
Formulation The MMP23B solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSYTLTPAR LRWDHFNLTY RILSFPRNLL SPRETRRALA AAFRMWSDVS PFSFREVAPE QPSDLRIGFY PINHTDCLVS ALHHCFDGPT GELAHAFFPP HGGIHFDDSE YWVLGPTRYS WKKGVWLTDL VHVAAHEIGH ALGLMHSQHG RALMHLNATL RGWKALSQDE LWGLHRLYG.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution
​

References

Not Available
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MMP23B
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