MMP1 sf9

Alternative Names: Not Available

MMP-1 is an enzyme that has the ability to break down various substrates, including several types of collagens, cytokines, and other proteins. One important function of MMP-1 is its role in breaking down fibrillar collagens during extracellular matrix remodeling. MMP-1 is expressed in various cell types such as fibroblasts, keratinocytes, endothelial cells, monocytes, and macrophages. The enzyme can be divided into different domains, including a prodomain that is cleaved upon activation, a catalytic domain containing a zinc binding site, and a carboxyl terminal domain. MMP-1 is part of a group of genes that localize to chromosome 11q22.3.

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  • Sku: PSB-enz-989-2µg
  • Vendor: ProSpec-Tany
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Safety Data Sheet
UniProt Listing
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Product Details

Product Description

Recombinant Human Matrix Metalloproteinase-1, sf9 is a member of the matrix metalloproteinase family, which plays a key role in the breakdown of extracellular matrix proteins. This enzyme is commonly used in research and pharmaceutical applications due to its ability to cleave various substrates. With a molecular weight of approximately 28 kDa, Recombinant Human Matrix Metalloproteinase-1, sf9 is a valuable tool for studying the mechanisms of tissue remodeling and disease progression.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System Sf9 - Baculovirus cells. 
Purity 95% by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) No
Molecular Weight
 53.1 kDa
Structure Dimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Frozen
Formulation MMP1 protein solution (0.25mg/ml) containing 20mM MES buffer (pH 5.5), 10mM CaCl2, 100 mM NaCl, 0.05% Brij35 and 30% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

HSFPATLETQ EQDVDLVQKY LEKYYNLKND GRQVEKRRNS GPVVEKLKQM QEFFGLKVTG KPDAETLKVM KQPRCGVPDV AQFVLTEGNP RWEQTHLTYR IENYTPDLPR ADVDHAIEKA FQLWSNVTPL TFTKVSEGQA DIMISFVRGD HRDNSPFDGP GGNLAHAFQP GPGIGGDAHF DEDERWTNNF REYNLHRVAA HELGHSLGLS HSTDIGALMY PSYTFSGDVQ LAQDDIDGIQ AIYGRSQNPV QPIGPQTPKA CDSKLTFDAI TTIRGEVMFF KDRFYMRTNP FYPEVELNFI SVFWPQLPNG LEAAYEFADR DEVRFFKGNK YWAVQGQNVL HGYPKDIYSS FGFPRTVKHI DAALSEENTG KTYFFVANKY WRYDEYKRSM DPGYPKMIAH DFPGIGHKVD AVFMKDGFFY FFHGTRQYKF DPKTKRILTL QKANSWFNCR KNLEHHHHHH.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution
​

References

Not Available
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MMP1 sf9
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