MMP1 (24-207)

Alternative Names: Interstitial collagenase, Fibroblast collagenase, Matrix metalloproteinase-1, MMP-1, MMP1, CLG, CLGN.

MMP-1 is an enzyme that has the ability to degrade various substrates, including different types of collagens, proteins, and other compounds. Its main role is in breaking down fibrillar collagens during extracellular matrix remodeling. MMP-1 is found in various cell types such as fibroblasts, keratinocytes, endothelial cells, monocytes, and macrophages. Structurally, MMP-1 consists of a prodomain, a catalytic domain with a zinc binding site, and a carboxyl terminal domain. This enzyme is encoded by genes that are located on chromosome 11q22.3.

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  • Sku: PSB-enz-1085-2µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Matrix Metalloproteinase-1 (24-207 a.a) is a member of the matrix metalloproteinase family, which plays a role in the breakdown of extracellular matrix in normal physiological processes such as tissue remodeling and wound healing. This specific recombinant protein consists of amino acids 24-207 and has a molecular weight of approximately 21.4 kDa. It is commonly used in research settings to study the enzymatic activity and substrate specificity of matrix metalloproteinase-1.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System HEK 293
Purity 95.0 % by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) No
Molecular Weight
21.2 kDa
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Lyophilized
Formulation MMP1 (24-207) filtered (0.4 µm) and lyophilized from 0.5mg/ml in PBS, pH7.5 and 5% (w/v) Threalose.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

CTCVPPHPQT AFCNSDLVIR AKFVGTPEVN QTTLYQRYEI KMTKMYKGFQ ALGDAADIRF VYTPAMESVC GYFHRSHNRS EEFLIAGKLQ DGLLHITTCS FVAPWNSLSL AQRRGFTKTY TVGCEECTVF PCLSIPCKLQ SGTHCLWTDQ LLQGSEKGFQ SRHLACLPRE PGLCTWQSLR SQIAHHHHHH.

Storage Instruction

Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C. Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.

Sample Prep Instruction

It is recommended to add deionized water to prepare a working stock solution of approximately 0.5mg/ml and let the lyophilized pellet dissolve completely.

References

Not Available

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MMP1 (24-207)

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