mMIP 1a, His

Alternative Names: Small inducible cytokine A3, SCYA3, SIS-alpha, SIS-beta, PAT 464.1, chemokine (C-C motif) ligand 3, CCL3, Macrophage inflammatory protein 1-alpha, MIP-1-alpha, MIP1A, G0/G1 switch regulatory protein 19-1, G0S19-1, G0S19-1 protein, Tonsillar lymphocyte LD78 alpha protein, LD78ALPHA, TY-5, Heparin-binding chemotaxis protein, L2G25B.

Macrophage Inflammatory Proteins (MIP) are chemokines that play a role in inflammation. In humans, the main forms are MIP-1a (CCL3) and MIP-1b (CCL4), which are produced by macrophages in response to bacterial endotoxins. These proteins activate granulocytes, leading to acute inflammation, and also stimulate the release of other pro-inflammatory cytokines from fibroblasts and macrophages. The genes for CCL3 and CCL4 are located on human chromosome 17.

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  • Sku: PSB-chm-008-2µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Product Details

Product Description

Recombinant Mouse Macrophage Inflammatory protein-1 alpha (CCL3), His Tag is a member of the chemokine family, specifically belonging to the CC chemokine subfamily. This protein plays a role in the immune response by attracting and activating macrophages and other immune cells. With a molecular weight of approximately 8.6 kDa, this recombinant protein is commonly used in research settings to study inflammation and immune system function.

Current Lead Time

7-14 Days

Product Specifications

Species
 Mouse
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 10.4 kDa
Structure Homodimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Frozen
Formulation MIP-1a protein solution (0.5mg/ml) containing 20mM Sodium citrate buffer (pH 3.5) and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSMAPYGAD TPTACCFSYS RKIPRQFIVD YFETSSLCSQ PGVIFLTKRN RQICADSKET WVQEYITDLE LNA.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution
​

References

Not Available
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mMIP 1a, His
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