mMIP 1a

Alternative Names: Small inducible cytokine A3, SCYA3, SIS-alpha, SIS-beta, CCL3, chemokine (C-C motif) ligand 3, MIP1A, Macrophage inflammatory protein 1-alpha, MIP-1-alpha, Tonsillar lymphocyte LD78 alpha protein, LD78ALPHA, G0/G1 switch regulatory protein 19-1, G0S19-1, G0S19-1 protein, TY-5, L2G25B, PAT 464.1.

MIP, or Macrophage Inflammatory Proteins, are chemokines that play a key role in inflammation. In humans, there are two main forms known as CCL3 and CCL4. These proteins are produced by macrophages in response to bacterial endotoxins. They can activate certain types of white blood cells and stimulate the release of other inflammatory molecules. The genes for CCL3 and CCL4 are both found on human chromosome 17.

  •
  • Sku: PSB-chm-320-2µg
  • Vendor: ProSpec-Tany
$60.00 USD
Shipping calculated at checkout.

Contact us directly for international purchases.

Title
Report Product Listing Issue (e.g. Missing Data, or Questions)
Safety Data Sheet
UniProt Listing
NCBI Link

Product Details

Product Description

Recombinant Mouse Macrophage Inflammatory protein-1 alpha (CCL3) is a chemokine belonging to the CC subfamily. It plays a role in the recruitment and activation of immune cells, particularly macrophages and T cells, in response to inflammation. With a molecular weight of approximately 8.8 kDa, CCL3 functions as a chemoattractant to promote the migration of immune cells to sites of infection or injury. Its ability to modulate immune responses makes it a valuable tool for studying inflammatory processes in various disease models.

Current Lead Time

7-14 Days

Product Specifications

Species
 Mouse
Expression System E. coli
Purity 99.0% by SDS-PAGE
Activity
 The Activity is calculated by the ability to chemoattract of Balb3/C splenocytes using 1-10ng/ml corresponding to a Specific Activity of 100,000-1,000,000IU/mg. The Activity is calculated by the ability to chemoattract of Balb3/C splenocytes using 1-10ng/ml corresponding to a Specific Activity of 100,000-1,000,000IU/mg.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 N/A
Structure Homodimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Lyophilized
Formulation The protein was lyophilized from 1mg/ml solution containing no additives.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

The sequence of the first five N-terminal amino acids was determined and was found to be, Ala-Pro-Tyr-Gly-Ala.

Storage Instruction

Lyophilized MIP-1a although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CCL3 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized Macrophage Inflammatory Protein-1a in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available
View full details

mMIP 1a
SUBHEADING

Recently viewed products