mLymphotactin

Alternative Names: Small inducible cytokine C1, XC chemokine ligand 1, Lymphotaxin, LPTN, LTN, Cytokine SCM-1, SCM-1, SCM1, SCM-1-alpha, SCM-1a, SCYC1, ATAC, XCL1

XCL1, a member of the XC chemokine family also known as lymphotactin, is a small cytokine found at high levels in the spleen, thymus, intestine, and peripheral blood leukocytes. It is also present at lower levels in the lung, prostate gland, and ovary. XCL1 is primarily produced by activated thymic and peripheral blood CD8+ T cells to attract other T cells. In humans, XCL1 is closely related to XCL2 and functions by binding to the XCR1 chemokine receptor to induce chemotactic responses.

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  • Sku: PSB-chm-037-50µg
  • Vendor: ProSpec-Tany
$400.00 USD
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Safety Data Sheet
UniProt Listing
NCBI Link

Product Details

Product Description

Recombinant Mouse Lymphotactin (XCL1) is a chemokine protein that belongs to the C family of chemokines. It plays a role in the immune response by attracting lymphocytes to sites of inflammation. XCL1 has a molecular weight of approximately 8.2 kDa. This protein is commonly used in research settings to study immune cell migration and inflammatory responses.

Current Lead Time

7-14 Days

Product Specifications

Species
 Mouse
Expression System E. coli
Purity 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE
Activity
 The ED50 as determined by a chemotaxis bioassay using human XCR1 transfected murine BaF3 cells is < 100 ng/ml, corresponding to a specific activity of > 1.0 × 104 IU/mg.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 10.1 kDa
Structure Dimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Frozen
Formulation Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH 7.4.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

VGTEVLEESS CVNLQTQRLP VQKIKTYIIW EGAMRAVIFV TKRGLKICAD PEAKWVKAAI KTVDGRASTR KNMAETVPTG AQRSTSTAIT LTG.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution
​

References

Not Available
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mLymphotactin
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