mLeptin tA PEG
Alternative Names: Not Available
- Sku: PSB-cyt-566-5µg
- Vendor: ProSpec-Tany
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Product Description
The Recombinant Pegylated Mouse Leptin Triple Antagonist, Pegylated, is a synthetic protein that belongs to the family of pegylated mouse leptin antagonists. With a weight of approximately [insert weight], this compound exhibits potent inhibitory effects on mouse leptin receptors, thereby modulating the signaling pathway associated with leptin. The pegylation process enhances the stability and prolongs the half-life of this antagonist, making it a promising therapeutic option for conditions related to dysregulated leptin signaling.
Current Lead Time
7-14 Days
Product Specifications
Species |
Mouse |
Expression System | E. coli |
Purity | 99.0% by SDS-PAGE |
Activity |
Leptin Antagonist Triple Mutant Mouse Recombinant half-life in circulation after SC injection was over 20 hours.Leptin Antagonist Triple Mutant Mouse Recombinant is capable of inhibiting leptin-induced proliferation of BAF/3 cells stably transfected with the long form of human leptin receptor. Leptin Antagonist Triple Mutant Mouse Recombinant in vitro activity is 5-6 fold lower than the non-pegylated antagonist, though in vivo it has profound weight gain effect (as compared to the non-pegylated antagonist), resulting mainly from increased food intake. |
Activity Assay | |
Animal Component Free (ACF) | Yes |
Molecular Weight |
N/A |
Structure | Contact for Details |
Endotoxin Concentration |
Not Available |
Purification Method | Not Available |
Form |
Lyophilized |
Formulation | The Mouse Leptin triple anatagonist was lyophilized from a concentrated (0.65mg/ml) solution with 0.003mM NaHCO3. |
*For Research Use Only
If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation.
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mLeptin tA PEG