MIP 4 His

Alternative Names: Small inducible cytokine A18, SCYA18, CCL18, chemokine (C-C motif) ligand 18, CKb7, Macrophage inflammatory protein 4, MIP-4, Pulmonary and activation-regulated chemokine, PARC, CC chemokine PARC, Alternative macrophage activation-associated CC chemokine 1, AMAC-1, AMAC1, Dendritic cell chemokine 1, DC-CK1, DCCK1.

CCL18 is a small cytokine belonging to the CC chemokine family, previously known as PARC. It is highly expressed in the lungs and at lower levels in lymphoid tissues. CCL18 is chemotactic for activated T cells and lymphocytes. The human gene for CCL18 has three exons and is located on chromosome 17.

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  • Sku: PSB-chm-339-1µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Macrophage Inflammatory protein-4 (CCL18), His-Tag is a protein belonging to the chemokine family. It plays a role in the immune response by attracting monocytes, dendritic cells, and lymphocytes to sites of inflammation. This protein has a molecular weight of approximately 8.7 kDa and is commonly used in research studies to investigate its role in inflammatory processes. The His-Tag allows for easy purification and detection of the protein in experimental settings.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
10.4 kDa
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The MIP-4 solution (0.25 mg/ml) contains 10mM Sodium Citrate pH3.5 and 10% Glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSHMQVGTN KELCCLVYTS WQIPQKFIVD YSETSPQCPK PGVILLTKRG RQICADPNKK WVQKYISDLK LNA.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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MIP 4 His

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