MIP 3b

Alternative Names: Small inducible cytokine A19, SCYA19, chemokine (C-C motif) ligand 19, CCL19, Macrophage inflammatory protein 3 beta, MIP-3- beta, MIP3B, MIP-3b, EBI1-ligand chemokine, ELC, Beta chemokine exodus-3, CK beta-11, CKb11, chemokine beta-11, MGC34433.

CCL19, also known as ELC and MIP-3-beta, belongs to the CC chemokine family. It is expressed mainly in thymus and lymph nodes, with lesser levels in other tissues. CCL19 acts by binding to the chemokine receptor CCR7, attracting immune cells like dendritic cells and B cells.

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  • Sku: PSB-chm-287-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Safety Data Sheet
UniProt Listing
NCBI Link

Product Details

Product Description

Recombinant Human Macrophage Inflammatory protein-3 beta (CCL19) is a chemokine belonging to the CC chemokine family. It plays a role in the immune response by attracting and activating immune cells such as dendritic cells and T cells. CCL19 has a molecular weight of approximately 8.9 kDa and is involved in the regulation of inflammation and immune cell trafficking. This chemokine is commonly used in research studies to investigate its role in various immune-related processes.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System E. coli
Purity 98% by SDS-PAGE
Activity
 The Activity of CCL19 is calculated by the ability to chemoattract Human T cells using a concentration of 7-40ng/ml corresponding to a Specific Activity of 25,000-143,000IU/mg. The Activity of CCL19 is calculated by the ability to chemoattract Human T cells using a concentration of 7-40ng/ml corresponding to a Specific Activity of 25,000-143,000IU/mg.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 N/A
Structure Homodimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Lyophilized
Formulation Lyophilized without any additives.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

GTNDAEDCCL SVTQKPIPGY IVRNFHYLLI KDGCRVPAVV FTTLRGRQLC APPDQPWVER IIQRLQRTSA KMKRRSS.

Storage Instruction

Lyophilized MIP-3b although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CCL19 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized Macrophage Inflammatory Protein-3b in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available
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MIP 3b
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