mIL36RN
Alternative Names: Not Available
- Sku: PSB-cyt-154-2µg
- Vendor: ProSpec-Tany
Contact us directly for international purchases.
Product Description
The Recombinant Mouse Interleukin-36 Receptor Antagonist is a protein that acts as an inhibitor of the Interleukin-36 receptor signaling pathway. Belonging to the cytokine receptor family, it plays a crucial role in modulating the immune response. With a molecular weight of approximately [insert weight], this protein binds to the Interleukin-36 receptor and prevents the activation of downstream signaling molecules, thereby attenuating the inflammatory response. Its significance lies in its ability to regulate immune reactions, making it a potential target for therapeutic interventions in various inflammatory diseases.
Current Lead Time
7-14 Days
Product Specifications
|
Species |
Mouse |
| Expression System | E. coli |
| Purity | 95% by SDS-PAGE |
|
Activity |
Fully biologically active when compared to standard. Measured by its ability to inhibit IL-36a, IL-36b or IL-36g induced IL-6 secretion by NIH-3T3 mouse embryonic fibroblast cells. The ED50 for this effect is typically 0.8-4ug/ml (corresponding to a specific activity of 250-125units/mg) in the presence of 15ng/ml of recombinant mouse IL-36b. Fully biologically active when compared to standard. Measured by its ability to inhibit IL-36a, IL-36b or IL-36g induced IL-6 secretion by NIH-3T3 mouse embryonic fibroblast cells. The ED50 for this effect is typically 0.8-4ug/ml (corresponding to a specific activity of 250-125units/mg) in the presence of 15ng/ml of recombinant mouse IL-36b. |
| Activity Assay | |
| Animal Component Free (ACF) | Yes |
|
Molecular Weight |
17.0 kDa |
| Structure | Monomer |
|
Endotoxin Concentration |
Not Available |
| Purification Method | Not Available |
|
Form |
Lyophilized |
| Formulation | Lyophilized from a 0.2µm filtered concentrated solution in PBS, pH 7.4. |
*For Research Use Only
If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation.
Have a question?
mIL36RN