mI TAC

Alternative Names: C-X-C motif chemokine 11, Cxcl11, I-TAC, Small-inducible cytokine B11, Scyb11.

CXCL11 is a small cytokine in the CXC chemokine family, highly expressed in peripheral blood leukocytes, pancreas, and liver, with moderate levels in thymus, spleen, and lung, and low levels in small intestine, placenta, and prostate. Its gene expression is strongly induced by IFN-g and IFN-b, and weakly induced by IFN-a. CXCL11 interacts with the chemokine receptor CXCR3, showing higher affinity than other ligands CXCL9 and CXCL10. Located on human chromosome 4, CXCL11 is chemotactic for activated T cells.

  •
  • Sku: PSB-chm-026-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
Shipping calculated at checkout.

Contact us directly for international purchases.

Title
Report Product Listing Issue (e.g. Missing Data, or Questions)
Safety Data Sheet
UniProt Listing
NCBI Link

Product Details

Product Description

Recombinant Mouse I-TAC (CXCL11) is a chemokine protein belonging to the CXC subfamily. It plays a role in immune response regulation and inflammation by inducing chemotaxis in activated T cells. With a molecular weight of approximately 8.8 kDa, this protein is commonly used in research studies to investigate its effects on immune cell migration and activation. Purchase Recombinant Mouse I-TAC (CXCL11) for your experiments today to further explore its functions in the immune system.

Current Lead Time

7-14 Days

Product Specifications

Species
 Mouse
Expression System E. coli
Purity 98.0 by SDS-PAGE
Activity
 Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using murine CXCR3 transfected 293 cells is in a concentration of 10-100 ng/ml corresponding to a specific activity of 10,000-100,000 IU/mg. Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using murine CXCR3 transfected 293 cells is in a concentration of 10-100 ng/ml corresponding to a specific activity of 10,000-100,000 IU/mg.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 N/A
Structure Dimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Lyophilized
Formulation I TAC protein was lyophilized from a 0.2 µm filtered concentrated solution in 10 mM Sodium Citrate, pH 4.0, with 600 mM NaCl.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

FLMFKQGRCL CIGPGMKAVK MAEIEKASVI YPSNGCDKVE VIVTMKAHKR QRCLDPRSKQ ARLIMQAIEK KNFLRRQNM.

Storage Instruction

Lyophilized I TAC although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution I TAC should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized I TAC in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available
View full details

mI TAC
SUBHEADING

Recently viewed products