mGRO1 KC, His

Alternative Names: Growth-regulated alpha protein, CXCL1, Platelet-derived growth factor-inducible protein KC, Secretory protein N51, KC, Fsp, N51, gro, Gro1, Mgsa, Scyb1, chemokine (C-X-C motif) ligand 1

Chemokine (C-X-C motif) ligand 1 (CXCL1) is a small cytokine that belongs to the CXC chemokine family. It has been given various names in the past, including GRO1 oncogene, Neutrophil-activating protein 3 (NAP-3), and melanoma growth stimulating activity, alpha (MSGA-a). CXCL1 is produced by human melanoma cells and has mitogenic properties that contribute to the development of melanoma. It is also secreted by macrophages, neutrophils, and epithelial cells and acts as a chemoattractant for neutrophils. Additionally, CXCL1 inhibits the migration of oligodendrocyte precursors, participates in angiogenesis, inflammation, wound healing, and tumorigenesis. Its effects are mediated by signaling through the chemokine receptor CXCR2. The gene for CXCL1 is located on human chromosome 4, along with genes for other CXC chemokines.

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  • Sku: PSB-chm-002-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Safety Data Sheet
UniProt Listing
NCBI Link

Product Details

Product Description

Recombinant Mouse GRO/KC (CXCL1), His Tag is a protein that belongs to the chemokine family. With a weight of approximately X kDa, this protein plays a significant role in immune response and inflammation. It is commonly used in research and pharmaceutical applications for its chemotactic properties. The recombinant form of this protein, produced through genetic engineering techniques, allows for easy purification and high yield, making it a valuable tool in various scientific studies.

Current Lead Time

7-14 Days

Product Specifications

Species
 Mouse
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 10.5 kDa
Structure Homodimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Frozen
Formulation GRO1 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 10% glycerol and 0.1M NaCl.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSHMAPIAN ELRCQCLQTM AGIHLKNIQS LKVLPSGPHC TQTEVIATLK NGREACLDPE APLVQKIVQK MLKGVPK.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution
​

References

Not Available
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mGRO1 KC, His
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