mGDA

Alternative Names: Guanine deaminase, Guanase, Guanine aminase, Guanine aminohydrolase, GAH, Guanine deaminase, Guanase, Guanine aminase, Guanine aminohydrolase, GAH.

GDA, belonging to the ATZ/TRZ family, is responsible for the hydrolytic deamination of guanine and plays a role in microtubule assembly. Various transcript variants encoding different isoforms of GDA have been discovered.

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  • Sku: PSB-enz-1058-1µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Mouse Guanine Deaminase is an enzyme that plays a significant role in nucleotide metabolism. Belonging to the guanine deaminase family, this enzyme catalyzes the deamination of guanine, converting it into xanthine. With a molecular weight of approximately X kDa, Recombinant Mouse Guanine Deaminase is involved in maintaining the balance of nucleotide pools and regulating purine metabolism. Its precise functions and mechanisms are of great interest in various research fields, including drug development and understanding genetic disorders.

Current Lead Time

7-14 Days

Product Specifications

Species
Mouse
Expression System E. coli
Purity 95.0 % by SDS-PAGE
Activity
Specific activity is > 4,000 pmol/min/ug, and is defined asthe amount of enzyme that convert guanine to xanthine per minute at pH 8.0 at 37°C.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
53.4 kDa
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation GDA protein solution (0.5mg/ml) containing 20mM Tris-HCl(pH8.0), 0.15M NaCl, 1mM DTT and 10% glycerol .

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSMCAARTP PLALVFRGTF VHSTWTCPME VLRDHLLGVS DSGKIVFLEE SSQQEKLAKE WCFKPCEIRE LSHHEFFMPG LVDTHIHAPQ YAFAGSNVDL PLLEWLNKYT FPTEQRFRST DVAEEVYTRV VRRTLKNGTT TACYFGTIHT DSSLILAEIT DKFGQRAFVG KVCMDLNDTV PEYKETTEES VKETERFVSE MLQKNYPRVK PIVTPRFTLS CTETLMSELG NIAKTHDLYI QSHISENREE IEAVKSLYPS YKNYTDVYDK NNLLTNKTVM AHGCYLSEEE LNIFSERGAS IAHCPNSNLS LSSGLLNVLE VLKHKVKIGL GTDVAGGYSY SMLDAIRRAV MVSNVLLINK VNEKNLTLKE VFRLATLGGS QALGLDSEIG NFEVGKEFDA LLINPRASDS PIDLFYGDFV GDISEAVIQK FLYLGDDRNI EEVYVGGKQV VPFSSSV.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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mGDA

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