mCTSZ, Active

Alternative Names: Cathepsin Z, Cathepsin X, Cathepsin Z1, Cathepsin P, Cathepsin Y, Cathepsin IV, Cathepsin B2, Cysteine-Type Carboxypeptidase, Lysosomal Carboxypeptidase B, Carboxypeptidase LB, EC 3.4.18.1, Preprocathepsin P, CTSX.

Cathepsin-Z (CTSZ) is a lysosomal cysteine proteinase in the peptidase C1 family. It is also known as cathepsin X and cathepsin P, and exhibits carboxy-monopeptidase and carboxy-dipeptidase activities. CTSZ is widely expressed in cancer cell lines and tumors, playing a role in tumorigenesis like other family members.

  •
  • Sku: PSB-enz-1108-1µg
  • Vendor: ProSpec-Tany
$60.00 USD
Shipping calculated at checkout.

Contact us directly for international purchases.

Title
Report Product Listing Issue (e.g. Missing Data, or Questions)
Safety Data Sheet
UniProt Listing
NCBI Link

Product Details

Product Description

Recombinant Mouse Cathepsin-Z, Active is a member of the cathepsin family of proteases. This enzyme plays a key role in protein degradation and turnover within cells. With a molecular weight of approximately 35 kDa, this active form of mouse cathepsin-Z is commonly used in research settings to study its enzymatic activity and potential therapeutic applications. Its precise mechanism of action and substrate specificity make it a valuable tool for investigating cellular processes and disease pathways.

Current Lead Time

7-14 Days

Product Specifications

Species
 Mouse
Expression System Sf9 - Baculovirus cells
Purity 95% by SDS-PAGE
Activity
 Specific activity is > 3,000 pmol/min/ug. One unit will convert 1 pmole of Mca-PLGL-Dpa-AR-NH2 to MCA- Pro-Leu-OH per minute at pH 3.5 at 25°C.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 N/A
Structure Dimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Frozen
Formulation The CTSZ solution (0.5 mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

ARARLYFRSG QTCYHPIRGD QLALLGRRTY PRPHEYLSPA DLPKNWDWRN VNGVNYASVTRNQHIPQYCG SCWAHGSTSA MADRINIKRK GAWPSILLSV QNVIDCGNAG SCEGGNDLPVWEYAHKHGIP DETCNNYQAK DQDCDKFNQC GTCTEFKECH TIQNYTLWRV GDYGSLSGREKMMAEIYANG PISCGIMATE MMSNYTGGIY AEHQDQAVIN HIISVAGWGV SNDGIEYWIVRNSWGEPWGE KGWMRIVTST YKGGTGDSYN LAIESACTFG DPIVLEHHHH HH

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution
​

References

Not Available
View full details

mCTSZ, Active
SUBHEADING

Recently viewed products