MCP1 His

Alternative Names: Small inducible cytokine A2, SCYA2, CCL2, chemokine (C-C motif) ligand 2, MCP1, Monocyte chemotactic protein 1, MCP-1, Monocyte chemoattractant protein 1, Monocyte chemotactic and activating factor, MCAF, Monocyte secretory protein JE, HC11, GDCF-2, GDCF-2 HC11, SMC-CF, HSMCR30, MGC9434.

CCL2, also known as MCP-1, is a small cytokine belonging to the CC chemokine family. It is found in the bone and plays a role in recruiting immune cells to sites of tissue injury and infection. CCL2 is expressed by mature osteoclasts and osteoblasts and is regulated by NF?B. It is produced as a precursor protein containing signal and mature peptides. CCL2 is a monomeric polypeptide with a molecular weight of approximately 13kDa. The gene for CCL2 is located on chromosome 17 in humans, and its cell surface receptors are CCR2 and CCR5.

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  • Sku: PSB-chm-246-10µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Product Details

Product Description

Recombinant Human Monocyte Chemotactic Protein-1/MCAF (CCL2), His Tag is a protein belonging to the chemokine family, specifically the CC chemokine subfamily. It plays a role in the recruitment and activation of monocytes and other leukocytes in response to inflammation. This protein has a molecular weight of approximately 13 kDa and is commonly used in research and therapeutic applications for its chemotactic properties.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 N/A
Structure Monomer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Frozen
Formulation The His Tag MCP-1 protein (1mg/ml) solution contains 20mM Tris-HCL pH-8.0, 1mM DTT and 20% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MQPDAINAPV TCCYNFTNRK ISVQRLASYR RITSSKCPKE AVIFKTIVAK EICADPKQKW VQDSMDHLDK QTQTPKT.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution
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References

Not Available
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MCP1 His
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