MCP1 HEK

Alternative Names: CCL2, C-C motif chemokine 2, GDCF-2, HSMCR30, JE, HC11, MCAF, MCP-1, MCP1, Scya2, Sigje, SMC-CF, Immediate-early serum-responsive protein JE, Monocyte chemoattractant protein 1, Small-inducible cytokine A2.

CCL2, also known as MCP-1, is a small cytokine in the CC chemokine family. It is produced by mature osteoclasts and osteoblasts in bones under the control of NF?B. CCL2 recruits monocytes to sites of tissue injury and infection by binding to receptors CCR2 and CCR5. It is a monomeric polypeptide with a molecular weight of approximately 13kDa and is located on chromosome 17 in humans.

Skip to product information
  • Sku: PSB-chm-048-2µg
  • Vendor: ProSpec-Tany
$60.00 USD
 per 
Shipping calculated at checkout.

Contact us directly for international purchases.

Title

Product Details

Product Description

Recombinant Human Monocyte Chemotactic Protein-1 (MCP-1), also known as Monocyte Chemoattractant Protein-1 (MCAF) or C-C motif chemokine ligand 2 (CCL2), is a member of the chemokine family. This protein plays a key role in the recruitment of monocytes to sites of inflammation and infection. Produced in Human Embryonic Kidney (HEK) cells, Recombinant Human MCP-1 has a molecular weight of approximately 13 kDa. Its ability to regulate immune responses and promote monocyte migration makes it a valuable tool for research in immunology and inflammation.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System HEK 293
Purity 90% by SDS-PAGE
Activity
Measured its ability to chemoattract using THP-1 human acute monocytic leukemia cells. The ED50 range ≤ 30 ng/ml.
Activity Assay
Animal Component Free (ACF) No
Molecular Weight
N/A
Structure Dimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The MCP1 solution (0.25mg/1ml) contains phosphate buffered saline (pH7.4) and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

QPDAINAPVT CCYNFTNRKI SVQRLASYRR ITSSKCPKEA VIFKTIVAKE ICADPKQKWV QDSMDHLDKQ TQTPKTHHHH HH

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

View full details

MCP1 HEK

SUBHEADING

Recently viewed products