mBcl-XL

Alternative Names: Bcl-XL, Bcl-X(L), BclXL

Bcl-XL is a transmembrane protein found in the mitochondria of long-lived and postmitotic cells, such as adult brain cells. It plays a role in the signal transduction pathway of FAS-Ligand. Bcl-XL is an anti-apoptotic protein and a member of the Bcl-2 family, which can form heterodimers and regulate apoptosis. Bcl-XL is involved in the survival of cancer cells, making it a key monitor of cell suicide. It acts as a survival protein by repressing cell death.

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  • Sku: PSB-pro-1362-10µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Safety Data Sheet
UniProt Listing
NCBI Link

Product Details

Product Description

Recombinant Mouse B-Cell Leukemia/Lymphoma XL is a genetically engineered protein used in scientific research to study B-cell leukemia and lymphoma. Belonging to the family of recombinant proteins, it plays a significant role in understanding the molecular mechanisms underlying these diseases. With a specific focus on B-cell malignancies, this protein aids in elucidating the pathogenesis, progression, and potential therapeutic targets associated with leukemia and lymphoma. Weighing approximately [insert weight], Recombinant Mouse B-Cell Leukemia/Lymphoma XL offers researchers a valuable tool to further investigate these conditions in a controlled laboratory setting.

Current Lead Time

7-14 Days

Product Specifications

Species
 Mouse
Expression System E. coli
Purity 97.0% by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 23.7 kDa
Structure Homodimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Lyophilized
Formulation Bcl-XL Mouse was lyophilized from a 0.2µm filtered concentrated solution in 1×PBS, pH 7.4 and 5% Trehalose.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

SQSNRELVVD FLSYKLSQKG YSWSQFSDVE ENRTEAPEET EAERETPSAI NGNPSWHLAD SPAVNGATGH SSSLDAREVI PMAAVKQALR EAGDEFELRY RRAFSDLTSQ LHITPGTAYQ SFEQVVNELF RDGVNWGRIV AFFSFGGALC VESVDKEMQV LVSRIASWMA TYLNDHLEPW IQENGGWDTF VDLYGNNAAA ESRKGQERFN R.

Storage Instruction

Lyophilized Bcl-XL although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Bcl-XL should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized Bcl-XL in sterile 18M-cm H₂O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available
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mBcl-XL
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