MAT2B

Alternative Names: DTDP-4-keto-6-deoxy-D-glucose 4-reductase, MAT-II, MAT-IIbeta, MAT II beta, Methionine adenosyltransferase 2 subunit beta, Methionine adenosyltransferase II beta, MAT2-beta, MAT2-B, MAT2-B, MAT2B, MAT2B, MGC12237, MSTP045, Nbla02999, SDR23E1, TGR, UNQ2435/PRO4995.

MAT2B, a member of the methionine adenosyltransferase family, plays a key role in the biosynthesis of S-adenosylmethionine by catalyzing the conversion of methionine and ATP. As the regulatory beta subunit of MAT, increased expression of MAT2B in hepatoma cell lines leads to elevated DNA synthesis and promotes cell proliferation.

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  • Sku: PSB-enz-461-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Safety Data Sheet
UniProt Listing
NCBI Link

Product Details

Product Description

Recombinant Human Methionine Adenosyltransferase II, Beta is an enzyme that belongs to the transferase family. It plays a key role in the biosynthesis of S-adenosylmethionine, a critical molecule involved in various cellular processes. This enzyme has a molecular weight of approximately 38 kDa and is essential for maintaining proper methylation reactions within the cell. Its recombinant form is commonly used in research and biotechnology applications for studying methionine metabolism and related pathways.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 N/A
Structure Homodimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Frozen
Formulation The MAT2B protein solution contains 20mM Tris-HCl, pH-8, 1mM DTT, 1mM EDTA and 10% Glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MPEMPEDMEQ EEVNIPNRRV LVTGATGLLG RAVHKEFQQN NWHAVGCGFR RARPKFEQVN LLDSNAVHHI IHDFQPHVIV HCAAERRPDV VENQPDAASQ LNVDASGNLA KEAAAVGAFL IYISSDYVFD GTNPPYREED IPAPLNLYGK TKLDGEKAVL ENNLGAAVLR IPILYGEVEK LEESAVTVMF DKVQFSNKSA NMDHWQQRFP THVKDVATVC RQLAEKRMLD PSIKGTFHWS GNEQMTKYEM ACAIADAFNL PSSHLRPITD SPVLGAQRPR NTQLDCSKLE TLGIGQRTPF RIGIKESLWP FLIDKRWRQT VFH.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution
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References

Not Available
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MAT2B
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