mAPOA1

Alternative Names: Not Available

APOA1, also known as Apolipoprotein A-1, plays a crucial role in lipid metabolism as the primary protein component of HDL in the plasma. It aids in removing cholesterol from tissues and transporting it to the liver for excretion. APOA1 also functions as a cofactor for LCAT, facilitating the formation of most plasma cholesteryl esters. Additionally, APOA1 is involved in activating sperm motility within the SPAP complex. The APOA1 gene is closely related to two other apolipoprotein genes on chromosome 11. Mutations in the APOA1 gene are associated with HDL deficiency, Tangier disease, and systemic non-neuropathic amyloidosis. Higher levels of APOA1 have been linked to asthma and atopy.

  •
  • Sku: PSB-cyt-891-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
Shipping calculated at checkout.

Contact us directly for international purchases.

Title
Report Product Listing Issue (e.g. Missing Data, or Questions)
Safety Data Sheet
UniProt Listing
NCBI Link

Product Details

Product Description

Recombinant Mouse Apolipoprotein A-I is a protein belonging to the apolipoprotein family, specifically involved in lipid metabolism and transport. With a molecular weight of approximately 28 kDa, this protein plays a crucial role in the regulation of cholesterol homeostasis and cardiovascular health. Recombinant Mouse Apolipoprotein A-I is commonly used in research studies to investigate its function in lipid metabolism and its potential therapeutic applications in cardiovascular diseases.

Current Lead Time

7-14 Days

Product Specifications

Species
 Mouse
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 30.3 kDa
Structure Homodimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Frozen
Formulation APOA1 protein solution (1mg/ml) containing Phosphate buffered saline (pH7.4), 20% glycerol and 1mM DTT.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSDEPQSQW DKVKDFANVY VDAVKDSGRD YVSQFESSSL GQQLNLNLLE NWDTLGSTVS QLQERLGPLT RDFWDNLEKE TDWVRQEMNK DLEEVKQKVQ PYLDEFQKKW KEDVELYRQK VAPLGAELQE SARQKLQELQ GRLSPVAEEF RDRMRTHVDS LRTQLAPHSE QMRESLAQRL AELKSNPTLN EYHTRAKTHL KTLGEKARPA LEDLRHSLMP MLETLKTQVQ SVIDKASETL TAQ.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution
​

References

Not Available
View full details

mAPOA1
SUBHEADING

Recently viewed products