LHPP

Alternative Names: Phospholysine phosphohistidine inorganic pyrophosphate phosphatase, LHPP, hLHPP, HDHD2B.

LHPP is a member of the HAD-like hydrolase superfamily that is capable of hydrolyzing oxygen-phosphorus bonds in inorganic pyrophosphate, as well as nitrogen-phosphorus bonds in phospholysine, phosphohistidine, and imidodiphosphate. It is primarily found in the liver, kidney, and to a lesser extent in the brain.

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  • Sku: PSB-enz-575-2µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Phospholysine Phosphohistidine Inorganic Pyrophosphate Phosphatase is an enzyme that belongs to the phosphatase family, specifically targeting phospholysine, phosphohistidine, and inorganic pyrophosphate substrates. With a molecular weight of approximately 45 kDa, this enzyme plays a critical role in catalyzing the hydrolysis of phospholysine and phosphohistidine residues, as well as inorganic pyrophosphate, thereby regulating various cellular processes. Its recombinant form offers researchers a valuable tool for studying the mechanisms underlying these biochemical reactions.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
33.5 kDa
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The LHPP solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 10% glycerol and 0.1M NaCl.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MRGSHHHHHP WYASMTGGQQ MGRDLYDDDD KDRWGSHMAP WGKRLAGVRG VLLDISGVLY DSGAGGGTAI AGSVEAVARL KRSRLKVRFC TNESQKSRAE LVGQLQRLGF DISEQEVTAP APAACQILKE QGLRPYLLIH DGVRSEFDQI DTSNPNCVVI ADAGESFSYQ NMNNAFQVLM ELEKPVLISL GKGRYYKETS GLMLDVGPYM KALEYACGIK AEVVGKPSPE FFKSALQAIG VEAHQAVMIG DDIVGDVGGA QRCGMRALQV RTGKFRPSDE HHPEVKADGY VDNLAEAVDL LLQHADK.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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LHPP

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