Leuprorelin

Alternative Names: Leuprorelin, Leuprolide.

Leuprorelin, also known as leuprolide acetate, is a type of drug called a gonadotropin-releasing hormone agonist. It works by continuously stimulating receptors in the pituitary gland for this hormone. This initially leads to increased activity (flare), but eventually reduces the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) by the pituitary gland (downregulation). This drug is commonly used in the treatment of hormone-responsive cancers like prostate and breast cancer, as well as estrogen-dependent conditions such as endometriosis or uterine fibroids. It can also be used to treat precocious puberty and regulate ovarian stimulation during in-vitro fertilization (IVF).

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  • Sku: PSB-hor-260-5mg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Human Leuprolide, also known as Leuprolide Acetate, is a synthetic analog of gonadotropin-releasing hormone (GnRH). Belonging to the class of medications called GnRH agonists, it primarily acts by suppressing the production of certain hormones in the body. This medication is commonly used in the treatment of various conditions such as prostate cancer, endometriosis, and precocious puberty. With a molecular weight of approximately 1269.46 g/mol, Human Leuprolide is administered via injection and is available in different formulations to suit specific medical requirements.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System Contact for Details
Purity 98% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) No
Molecular Weight
N/A
Structure Dimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Lyophilized
Formulation The Leuprorelin was lyophilized from a concentrated (1mg/ml) solution with no additives.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

pGlu-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHEt.

Storage Instruction

Lyophilized Leoprolide although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Leuprorelin should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized Leoprolide in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available

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Leuprorelin

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